SCHEMBL7864623

SCHEMBL7864623

C=CCc1c(O)cccc1N(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.38
GABRB2 P47870 4/20 0.38
APP P05067 3/20 0.38
PTPN1 P18031 1/20 0.38
SRD5A1 P18405 1/20 0.37
MTNR1A P48039 1/20 0.36
MAPT P10636 4/20 0.36
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
PLEC Q15149 1/20 0.36
GAA P10253 2/20 0.35
XDH P47989 1/20 0.35
ACHE P22303 2/20 0.35
MCL1 Q07820 1/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
ALDH2 P05091 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9288739 0.81 GABRA1 (0.37) GABRA1GABRB2PTPN1SRD5A1MTNR1A
SCHEMBL69556 0.80 GABRA1 (0.48) GABRA1GABRB2SRD5A1MTNR1AMAPT
SCHEMBL27474264 0.77 MAPT (0.40) GABRA1APPMAPTKDM4EALDH1A1
SCHEMBL129735 0.77 MAPT (0.40) GABRA1GABRB2APPMAPTKDM4E
SCHEMBL29284646 0.76 XDH (0.37) GABRA1GABRB2APPPTPN1SRD5A1
SCHEMBL27958462 0.76 TRPA1 (0.45) GABRA1GABRB2SRD5A1MTNR1AMAPT
SCHEMBL30023289 0.76 TRPA1 (0.45) GABRA1GABRB2SRD5A1MTNR1AMAPT
SCHEMBL2321816 0.76 TRPA1 (0.45) GABRA1GABRB2SRD5A1MTNR1AMAPT
SCHEMBL10587406 0.75 GABRA1 (0.53) GABRA1GABRB2SRD5A1MTNR1AMAPT
SCHEMBL6690960 0.75 GABRA1 (0.44) GABRA1GABRB2SRD5A1MTNR1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1151853-A1 EASILY DELAMINATABLE LAMINATE AND RESIN COMPOSITION FOR USE THEREIN Sumitomo Chemical Company, Limited (JP) 2001-11-07 EP disclosed