SCHEMBL27474264

SCHEMBL27474264

CN(C)c1cccc(O)c1CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
KDM4E B2RXH2 4/20 0.40
GAA P10253 3/20 0.40
MCL1 Q07820 1/20 0.39
EP300 Q09472 1/20 0.38
KAT2B Q92831 1/20 0.38
KAT8 Q9H7Z6 1/20 0.38
APP P05067 4/20 0.38
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
ALDH1A1 P00352 5/20 0.36
TSHR P16473 3/20 0.36
TP53 P04637 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 3/20 0.34
CA2 P00918 2/20 0.34
LMNA P02545 3/20 0.33
HTR2A P28223 2/20 0.33
EGFR P00533 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129735 0.83 MAPT (0.40) MAPTKDM4EGAAMCL1EP300
SCHEMBL5134430 0.80 GAA (0.38) MAPTKDM4EGAAMCL1EP300
SCHEMBL8791509 0.79 GAA (0.40) MAPTKDM4EGAAMCL1GABRA1
SCHEMBL14682132 0.79 MAPT (0.36) MAPTKDM4EGAAMCL1EP300
SCHEMBL7864623 0.77 GABRA1 (0.38) MAPTKDM4EGAAMCL1EP300
SCHEMBL4551579 0.77 ALDH1A1 (0.47) MAPTKDM4EAPPGABRA1GABRG2
SCHEMBL27523521 0.74 MGLL (0.44) MCL1EP300KAT2BKAT8HTR2A
SCHEMBL27341878 0.74 SIGMAR1 (0.47) MCL1ALOX15L3MBTL1
SCHEMBL28633909 0.73 KCNH2 (0.45) MCL1ALDH1A1RECQL
SCHEMBL5494774 0.73 ALDH1A1 (0.52) MAPTKDM4EGAAMCL1EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100439939-C Plastic lenses and primer composition used for coating the same NIPPON ARC CO LTD (JP) 2008-12-03 CN disclosed
CN-1754108-A Method for producing article having been subjected to low reflection treatment, solution for forming low reflection layer and article having been subjected to low reflection treatment SDC TECH ASIA CO LTD (JP) 2006-03-29 CN disclosed
CN-1174262-C Plastic lens �ձ�ARC��ʽ���� 2004-11-03 CN disclosed
CN-1314934-A Coated article NIPPON ARC CO LTD (JP) 2001-09-26 CN disclosed
CN-1231031-A Plastic lenses and primer composition used for coating the same NIPPON ARC CO LTD (JP) 1999-10-06 CN disclosed