Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4061727 | 0.86 | JAK2 (0.56) | JAK2JAK3GLAKEAP1KMT2A | |
| SCHEMBL7868892 | 0.85 | CA2 (0.46) | SLC40A1GLO1GLACA2KEAP1 | |
| SCHEMBL4061858 | 0.76 | JAK2 (0.48) | JAK2JAK3SLC40A1GLO1GLA | |
| SCHEMBL5317913 | 0.75 | JAK2 (0.74) | JAK2JAK3KMT2AMAPTKDM4E | |
| SCHEMBL4064582 | 0.75 | GLA (0.52) | GLAKMT2AMAPTKDM4EMAPK1 | |
| SCHEMBL4072266 | 0.73 | RAB9A (0.55) | JAK2JAK3GLO1GLAKMT2A | |
| SCHEMBL784141 | 0.70 | KEAP1 (0.66) | SLC40A1GLO1KEAP1NFE2L2KMT2A | |
| SCHEMBL4059196 | 0.69 | ALDH1A1 (0.53) | SLC40A1GLO1GLAKMT2AMAPT | |
| SCHEMBL15881331 | 0.67 | NAPRT (0.62) | SLC40A1GLO1CA2KEAP1NFE2L2 | |
| SCHEMBL21960091 | 0.67 | NAPRT (0.57) | SLC40A1GLO1KEAP1NFE2L2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303814-B1 | N-[1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC | 2001-10-16 | — | — | US | disclosed |
| EP-0877745-B1 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-25 | — | — | EP | disclosed |
| US-6130335-A | N-([1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2000-10-10 | — | — | US | disclosed |
| US-6005108-A | POST-EMERGENCE TOTAL VEGETATION CONTROL OR SELECTIVE CONTROL OF WEEDS IN WHEAT, RICE AND OIL-SEED RAPE CROPS | JOHNSON TIMOTHY C (US) | 1999-12-21 | — | — | US | disclosed |
| US-5965490-A | NOVEL COMPOUNDS WITH IMPROVED SELECTIVITY TO VALUABLE CROPS AND IMPROVED TOXICOLOGICAL AND ENVIRONMENTAL ATTRIBUTES; APPLYING TO CONTROL WEEDS BY EITHER PREEMERGENCE OR POSTEMERGENCE APPLICATION | DOW AGROSCIENCES LLC (US) | 1999-10-12 | — | — | US | disclosed |