Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605131 | 0.80 | HTR1A (0.43) | HTR1A | |
| SCHEMBL7609736 | 0.77 | CYP19A1 (0.46) | DRD1HTR2C | |
| SCHEMBL7607644 | 0.75 | CYP19A1 (0.46) | HTR2CHTR2BSIGMAR1 | |
| SCHEMBL8865945 | 0.74 | HTR1A (0.41) | HTR1A | |
| SCHEMBL8865285 | 0.72 | GID4 (0.50) | HTR2CSIGMAR1 | |
| SCHEMBL8865242 | 0.71 | CHRNA7 (0.41) | — | |
| SCHEMBL7604210 | 0.70 | ADRA1A (0.38) | HTR2B | |
| Hydrochloric Acid SCHEMBL7604517 | 0.69 | ADRA1A (0.37) | HTR2B | |
| SCHEMBL8865794 | 0.68 | ADRA1A (0.37) | — | |
| SCHEMBL8866074 | 0.68 | ADRA1A (0.45) | PARP1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313311-B1 | ADRENERGIC STIMULANTS FOR POTENTIATING ANESTHETICS PRIOR TO SURGERY; HYPOTENSIVE AGENTS, ANALGESICS, ANTIISCHEMIC AGENTS; NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | ORION CORPORATION (FI) | 2001-11-06 | — | — | US | disclosed |
| CN-1068592-C | Imidazole derivatives having affinity for alpha 2 receptors activity | ORION YHTYMAE OY (FI) | 2001-07-18 | — | — | CN | disclosed |
| EP-0888309-A1 | IMIDAZOLE DERIVATIVES HAVING AFFINITY FOR ALPHA2 RECEPTORS ACTIVITY | ORION CORPORATION (FI) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997012874-A1 | IMIDAZOLE DERIVATIVES HAVING AFFINITY FOR ALPHA2 RECEPTORS ACTIVITY | Orion-Yhtymä Oy (FI) | 1997-04-10 | — | — | WO | disclosed |