Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609736 | 0.94 | CYP19A1 (0.46) | GID4CYP19A1CHRNA7SRD5A1HTR2C | |
| SCHEMBL8865423 | 0.87 | KDM4C (0.41) | GID4 | |
| SCHEMBL7607644 | 0.83 | CYP19A1 (0.46) | CYP19A1CHRNA7SIGMAR1HTR2C | |
| SCHEMBL8865117 | 0.83 | SRD5A1 (0.39) | GID4SRD5A1 | |
| SCHEMBL8865242 | 0.82 | CHRNA7 (0.41) | CHRNA7 | |
| SCHEMBL8865718 | 0.81 | SRD5A1 (0.39) | SRD5A1HTR2C | |
| SCHEMBL8865200 | 0.81 | ESR1 (0.44) | CYP19A1SIGMAR1 | |
| SCHEMBL769063 | 0.78 | ADRA1A (0.55) | GID4 | |
| SCHEMBL8865945 | 0.78 | HTR1A (0.41) | — | |
| SCHEMBL7038653 | 0.77 | SIGMAR1 (0.49) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658938-A | HYPOTENSIVE AGENT, ANTIISCHMIC AGENTS | U C B S.A. (BE) | 1997-08-19 | — | — | US | claimed |
| EP-0717037-A1 | Substituted 1H-imidazoles having alpha 2-agonistic and alpha 1-antagonistic activity | U C B, S.A. (BE) | 1996-06-19 | — | — | EP | claimed |
| JP-8208622-A | — | — | None | — | — | JP | disclosed |
| US-5658938-A | HYPOTENSIVE AGENT, ANTIISCHMIC AGENTS | U C B S.A. (BE) | 1997-08-19 | — | — | US | disclosed |
| JP-H08208622-A | SUBSTITUTED 1H-IMIDAZOLE | UCB SA | 1996-08-13 | — | — | JP | disclosed |
| EP-0717037-A1 | Substituted 1H-imidazoles having alpha 2-agonistic and alpha 1-antagonistic activity | U C B, S.A. (BE) | 1996-06-19 | — | — | EP | disclosed |