Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323732 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CTSBCTRB1HCAR2MAPK1 | |
| SCHEMBL713212 | 0.76 | LTA4H (0.44) | ALDH1A1CTRB1KMT2A | |
| SCHEMBL729057 | 0.76 | LTA4H (0.44) | ALDH1A1CTRB1KMT2A | |
| Hydrochloric Acid SCHEMBL7273689 | 0.75 | LTA4H (0.43) | ALDH1A1CTRB1KMT2A | |
| Hydrochloric Acid SCHEMBL7273682 | 0.75 | LTA4H (0.43) | ALDH1A1CTRB1KMT2A | |
| Hydrochloric Acid SCHEMBL9515682 | 0.75 | LTA4H (0.43) | ALDH1A1CTRB1KMT2A | |
| Hydrochloric Acid SCHEMBL9515675 | 0.75 | LTA4H (0.43) | ALDH1A1CTRB1KMT2A | |
| SCHEMBL12483847 | 0.74 | LTA4H (0.38) | ALDH1A1CTRB1MAPK1POLBMBTPS1 | |
| SCHEMBL24795018 | 0.73 | ITGB3 (0.53) | CTSB | |
| SCHEMBL4178755 | 0.73 | ITGB3 (0.53) | CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077949-A2 | COMBINATIONS OF PROTEIN FARNESYLTRANSFERASE AND HMG COA REDUCTASE INHIBITORS AND THEIR USE TO TREAT CANCER | WARNER-LAMBERT COMPANY (US) | 2001-02-28 | — | — | EP | claimed |
| WO-1999058505-A2 | COMBINATIONS OF PROTEIN FARNESYLTRANSFERASE AND HMG COA REDUCTASE INHIBITORS AND THEIR USE TO TREAT CANCER | WARNER-LAMBERT COMPANY (US) | 1999-11-18 | — | — | WO | claimed |