Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7866984 | 0.99 | ALDH1A1 (0.44) | ALDH1A1PLAUKDM4EPOLBTDP1 | |
| SCHEMBL7866950 | 0.84 | LMNA (0.48) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7874134 | 0.83 | LMNA (0.47) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL7869922 | 0.80 | MAPT (0.56) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL7868840 | 0.79 | MAPT (0.55) | ALDH1A1KDM4EKMT2AMEN1RAB9A | |
| SCHEMBL7862182 | 0.77 | NPC1 (0.46) | ALDH1A1KDM4EPOLBTDP1KMT2A | |
| SCHEMBL8003660 | 0.77 | NPSR1 (0.50) | LMNARAB9A | |
| Hydrochloric Acid SCHEMBL7874098 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1PLAULMNA | |
| Hydrochloric Acid SCHEMBL7868488 | 0.75 | PLAU (0.45) | ALDH1A1PLAUKDM4EPOLBTDP1 | |
| SCHEMBL7870712 | 0.73 | BCAT2 (0.51) | ALDH1A1PLAUKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |