Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186106 | 0.71 | GRIN2B (0.56) | MC4RMEN1KMT2A | |
| SCHEMBL8118166 | 0.71 | MC4R (0.36) | MC4RJAK3HPGDALDH1A1MAN1B1 | |
| SCHEMBL15928065 | 0.68 | IDO1 (0.39) | MC4RIDO1MEN1KMT2ATHRB | |
| SCHEMBL6450191 | 0.68 | MAN1B1 (0.57) | MC4RHPGDALDH1A1ALOX12IDO1 | |
| SCHEMBL4924718 | 0.68 | HRH2 (0.53) | MC4RHPGDALDH1A1ALOX12MEN1 | |
| SCHEMBL8766756 | 0.68 | MAOA (0.48) | MC4RGBA1 | |
| SCHEMBL382152 | 0.68 | ALDH1A1 (0.40) | MC4RHPGDALDH1A1IDO1MEN1 | |
| SCHEMBL20787990 | 0.67 | TACR1 (0.45) | MC4RALDH1A1IDO1MEN1KMT2A | |
| SCHEMBL6204156 | 0.66 | FUCA1 (0.51) | MC4RALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10039743 | 0.66 | GRIN2B (0.50) | MC4RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310216-B1 | Special 3-azabicyclo[3.1.0]hexanes, method for producing and modifying the same, and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | disclosed |