Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867641 | 0.71 | MC4R (0.49) | MC4RHPGDMAPTMAN1B1JAK3 | |
| SCHEMBL30538977 | 0.63 | ALDH1A1 (0.37) | DPP4ALDH1A1 | |
| SCHEMBL15928065 | 0.62 | IDO1 (0.39) | MC4RKDM4ETSHRCYP3A4MAPT | |
| SCHEMBL9954167 | 0.60 | CYP1A2 (0.43) | KDM4EHPGDTSHRHSD17B10CYP3A4 | |
| SCHEMBL7870398 | 0.59 | ALDH1A1 (0.41) | MC4RTSHRALDH1A1 | |
| Diphenylmethane SCHEMBL29262556 | 0.59 | CALM1 (0.46) | MC4RALDH1A1 | |
| SCHEMBL19124635 | 0.59 | KDM4E (0.41) | KDM4EHPGDTSHRHSD17B10CYP3A4 | |
| SCHEMBL27755650 | 0.59 | MMP8 (0.41) | KDM4EHPGDTSHRHSD17B10CYP3A4 | |
| SCHEMBL382152 | 0.59 | ALDH1A1 (0.40) | MC4RHPGDTSHRCYP3A4MAPT | |
| SCHEMBL27892076 | 0.59 | CYP1A2 (0.42) | KDM4EHPGDTSHRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000026-A1 | SPECIAL 3-AZABICYCLO 3.1.0]HEXANES, METHOD FOR PRODUCING AND MODIFYING THE SAME, AND THEIR USE | Bayer Aktiengesellschaft (DE) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006368-A1 | SPECIAL 3-AZABICYCLO[3.1.0]HEXANES, METHOD FOR PRODUCING AND MODIFYING THE SAME, AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-11 | — | — | WO | disclosed |