Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630702 | 0.81 | CES2 (0.50) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL28748274 | 0.81 | CA1 (0.59) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL2721321 | 0.81 | TDP1 (0.59) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL8743220 | 0.79 | CES2 (0.48) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL2835113 | 0.79 | CES2 (0.48) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL25289477 | 0.79 | LMNA (0.55) | RAB9ANPC1MAPTKMT2ACYP1A2 | |
| SCHEMBL9212334 | 0.79 | ALDH1A1 (0.50) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL72654 | 0.78 | TSHR (0.58) | MAPTKMT2AMAPK1CES2CES1 | |
| SCHEMBL8742868 | 0.78 | CA1 (0.64) | NPC1MAPTMEN1KMT2ACES2 | |
| SCHEMBL248548 | 0.77 | CES2 (0.62) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138682-A1 | Novel water soluble c-ring analogues of 20 (s)-camptothecin | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-10-04 | — | — | EP | disclosed |
| US-6214836-B1 | VIRICIDES; ANTICANCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-04-10 | — | — | US | disclosed |
| US-6177439-B1 | ANTICARCINOGENIC AGENTS; VIRICIDES | REDDY'S RESEARCH FOUNDATION | 2001-01-23 | — | — | US | disclosed |
| US-5972955-A | ANTITUMOR AGENTS TREATING CANCER, VIRICIDES | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-10-26 | — | — | US | disclosed |