Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862207 | 0.85 | FFAR1 (0.57) | FFAR1FFAR4HTTNPSR1KDM4E | |
| SCHEMBL7868880 | 0.83 | FFAR1 (0.47) | FFAR1POLBKDM4EALDH1A1HAO1 | |
| SCHEMBL7867080 | 0.80 | MMP1 (0.49) | FFAR1POLBALDH1A1HAO1 | |
| SCHEMBL1551270 | 0.79 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL8446573 | 0.79 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL14993421 | 0.77 | FFAR1 (0.52) | FFAR1ALDH1A1ERN1 | |
| SCHEMBL27965841 | 0.74 | FFAR1 (0.55) | FFAR1ERN1 | |
| SCHEMBL1001018 | 0.73 | HSD11B1 (0.69) | POLBHTTNPSR1KDM4EALDH1A1 | |
| SCHEMBL30047851 | 0.73 | FFAR1 (0.62) | FFAR1HAO1ERN1 | |
| SCHEMBL3648381 | 0.73 | FFAR1 (0.62) | FFAR1HAO1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | claimed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |