Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446048 | 0.85 | MMP1 (0.69) | MMP1GAAMMP12KMT2AMMP2 | |
| SCHEMBL8451882 | 0.83 | FFAR1 (0.44) | FFAR1GAASLC7A11 | |
| SCHEMBL7868761 | 0.79 | FFAR1 (0.64) | FFAR1 | |
| SCHEMBL8451097 | 0.77 | MMP9 (0.57) | FFAR1MMP1GAAMMP12MMP2 | |
| SCHEMBL14993421 | 0.76 | FFAR1 (0.52) | FFAR1 | |
| SCHEMBL14992486 | 0.76 | PRMT1 (0.43) | FFAR1MMP13 | |
| SCHEMBL359770 | 0.74 | MMP1 (0.79) | MMP1GAAMMP12KMT2AMMP2 | |
| SCHEMBL8446269 | 0.74 | MEP1B (0.58) | MMP1GAAMMP12MMP2MMP3 | |
| SCHEMBL7671441 | 0.73 | LMNA (0.72) | GAA | |
| SCHEMBL27965841 | 0.73 | FFAR1 (0.55) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |