Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440132 | 0.86 | DRD1 (0.53) | DRD1PDE4APDE4BALDH1A1PDE4C | |
| SCHEMBL140841 | 0.86 | DRD1 (0.53) | DRD1PDE4APDE4BALDH1A1PDE4C | |
| SCHEMBL7418541 | 0.86 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DCYP4F2 | |
| SCHEMBL7538876 | 0.78 | ALDH1A1 (0.49) | DRD1PDE4APDE4BALDH1A1PDE4C | |
| SCHEMBL140472 | 0.76 | ALDH1A1 (0.70) | DRD1PDE4BALDH1A1TSHRKDM4E | |
| SCHEMBL1966450 | 0.76 | ALDH1A1 (0.70) | DRD1PDE4APDE4BALDH1A1PDE4C | |
| SCHEMBL31681723 | 0.76 | CA2 (0.48) | PDE4AALDH1A1TSHRKDM4EHTT | |
| SCHEMBL5026284 | 0.76 | CA2 (0.48) | PDE4AALDH1A1TSHRKDM4EHTT | |
| SCHEMBL5184347 | 0.76 | PDE4A (0.43) | DRD1PDE4APDE4BALDH1A1PDE4C | |
| SCHEMBL31619160 | 0.76 | ALDH1A1 (0.58) | DRD1PDE4BALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636025-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-07-18 | — | — | EP | disclosed |
| US-5811455-A | Compounds useful for treating allergic or inflammatory diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-22 | — | — | US | disclosed |