Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608698 | 0.77 | HPGD (0.36) | LNPEPLIPEHPGDSCN9AMRGPRX4 | |
| SCHEMBL5793193 | 0.72 | HPGD (0.44) | LIPEHPGDSCN9AMRGPRX4MAPK1 | |
| SCHEMBL23708686 | 0.72 | EPHX2 (0.48) | LIPEHPGDMAPK1KMT2ATSHR | |
| SCHEMBL24529873 | 0.72 | LNPEP (0.44) | LNPEPLIPEHPGDSCN9AFFAR1 | |
| SCHEMBL5763749 | 0.71 | HPGD (0.47) | HPGDSCN9AMRGPRX4MAPK1KMT2A | |
| SCHEMBL9895811 | 0.71 | LIPE (0.41) | LIPEHPGDMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL3159889 | 0.68 | HPGD (0.48) | LIPEHPGDMRGPRX4MAPK1KMT2A | |
| SCHEMBL10121582 | 0.67 | HPGD (0.38) | LIPEHPGDSCN9AMRGPRX4MAPK1 | |
| SCHEMBL9895397 | 0.67 | LNPEP (0.34) | LNPEP | |
| SCHEMBL22761804 | 0.66 | LTA4H (0.57) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122151-A1 | 3 -AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2010-10-28 | — | — | WO | disclosed |