Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PDE4A | P27815 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39222 | 0.96 | LMNA (0.54) | LMNASMN1; SMN2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL4303475 | 0.89 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL9917150 | 0.89 | LMNA (0.47) | LMNASMN1; SMN2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL10444894 | 0.80 | LMNA (0.37) | LMNASMN1; SMN2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL10522655 | 0.77 | LMNA (0.37) | LMNASMN1; SMN2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL10522528 | 0.77 | CRHR1 (0.37) | LMNASMN1; SMN2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL13588261 | 0.77 | NPSR1 (0.33) | LMNASMN1; SMN2KMT2ANPSR1MAPT | |
| SCHEMBL5671532 | 0.77 | MEN1 (0.36) | LMNASMN1; SMN2KMT2AGAANPSR1 | |
| SCHEMBL11285952 | 0.76 | LMNA (0.39) | LMNASMN1; SMN2PDE4ACYP1A2CYP2C19 | |
| SCHEMBL2906382 | 0.75 | NPSR1 (0.35) | LMNASMN1; SMN2KMT2ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316619-B1 | USED AS LIGHT STABILIZER FOR ORGANIC MATERIALS SUCH AS POLYETHYLENE AND POLYPROPYLENE; LOW MELTING POINT, BLEEDING RESISTANCE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| WO-1994000513-A1 | SUBSTITUTED PYRIMIDINES AND SUBSTITUTED TRIAZINES AS RUBBER-TO-METAL ADHESION PROMOTERS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| EP-0070386-B1 | NOVEL LIGHT STABILIZERS FOR POLYMERS | AMERICAN CYANAMID COMPANY (US) | 1989-01-11 | — | — | EP | disclosed |
| US-4461861-A | Polymer compositions stabilized with triazinyl-piperidine compounds | AMERICAN CYANAMID COMPANY (US) | 1984-07-24 | — | — | US | disclosed |
| US-4400505-A | Triazinyl-piperidines as light stabilizers for polymers | AMERICAN CYANAMID COMPANY (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0070386-A1 | Novel light stabilizers for polymers | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| EP-0005586-B1 | 2,4,6-TRIS-(SUBSTITUTED-AMINO)-S-TRIAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1982-04-28 | — | — | EP | disclosed |
| US-4269832-A | 2-/SUBSTITUTED-AMINO/-4,6-BIS/ALKYLAMINO/-5-TRIAZINES AS ANTIARTHRITIC AND ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-05-26 | — | — | US | disclosed |
| US-4261892-A | ANTIINFLAMMATORY, ANTIARTHRITIC | AMERICAN CYANAMID COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| EP-0005586-A1 | 2,4,6-Tris-(substituted-amino)-S-triazines, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-11-28 | — | — | EP | disclosed |