Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347806 | 0.84 | MEN1 (0.43) | MEN1LMNAKMT2AATML3MBTL1 | |
| SCHEMBL7387231 | 0.84 | NPC1 (0.32) | MEN1LMNAKMT2AELANE | |
| Pivalate SCHEMBL7874022 | 0.78 | MEN1 (0.34) | MEN1LMNAKMT2AATML3MBTL1 | |
| SCHEMBL7385357 | 0.76 | PTGS2 (0.42) | LMNA | |
| SCHEMBL7376958 | 0.69 | KMT2A (0.40) | MEN1LMNAKMT2A | |
| SCHEMBL13038658 | 0.69 | PPARA (0.37) | MEN1KMT2A | |
| SCHEMBL7379152 | 0.66 | MAOB (0.41) | MEN1LMNAKMT2A | |
| SCHEMBL7385350 | 0.63 | GAA (0.38) | LMNAKMT2AATML3MBTL1 | |
| SCHEMBL7351852 | 0.63 | ELANE (0.57) | MEN1LMNAKMT2AATML3MBTL1 | |
| SCHEMBL7345565 | 0.62 | MEN1 (0.45) | MEN1LMNAKMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | claimed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |