Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 7/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.30 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pivalate SCHEMBL8129979 | 0.82 | MEN1 (0.48) | MEN1KMT2ALMNAATML3MBTL1 | |
| SCHEMBL7385357 | 0.79 | PTGS2 (0.42) | LMNA | |
| SCHEMBL7870692 | 0.78 | MEN1 (0.31) | MEN1KMT2ALMNAATML3MBTL1 | |
| SCHEMBL7387231 | 0.78 | NPC1 (0.32) | MEN1KMT2ALMNANPC1ELANE | |
| SCHEMBL7376958 | 0.74 | KMT2A (0.40) | MEN1KMT2ALMNANPC1RAB9A | |
| Methane SCHEMBL7344826 | 0.73 | L3MBTL1 (0.46) | MEN1KMT2ALMNAATML3MBTL1 | |
| SCHEMBL7385350 | 0.72 | GAA (0.38) | KMT2ALMNAATML3MBTL1NPC1 | |
| Pivalate SCHEMBL7867130 | 0.71 | KEAP1 (0.39) | NPC1RAB9A | |
| SCHEMBL7379152 | 0.70 | MAOB (0.41) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL155788 | 0.63 | L3MBTL1 (0.56) | MEN1KMT2ALMNAATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | claimed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |