Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874157 | 0.85 | KMT2A (0.71) | KMT2AALDH1A1LMNAGAAPOLB | |
| SCHEMBL7862198 | 0.84 | LMNA (0.55) | KMT2AHTTMEN1ALDH1A1LMNA | |
| SCHEMBL7874068 | 0.83 | POLB (0.59) | KMT2AMMP1MEN1ALDH1A1LMNA | |
| SCHEMBL7870908 | 0.83 | ALDH1A1 (0.62) | KMT2AHTTNPSR1MMP1MEN1 | |
| SCHEMBL28897130 | 0.83 | KMT2A (0.53) | KMT2AHTTNPSR1MMP1MEN1 | |
| SCHEMBL28101227 | 0.83 | MAPT (0.59) | KMT2AHTTNPSR1MMP1LMNA | |
| SCHEMBL16144557 | 0.82 | KMT2A (0.57) | KMT2AHTTNPSR1MMP1MEN1 | |
| SCHEMBL7862156 | 0.81 | KMT2A (0.74) | KMT2AHTTNPSR1MMP1MEN1 | |
| SCHEMBL7862104 | 0.81 | HDAC1 (0.57) | KMT2AHTTNPSR1MMP1LMNA | |
| SCHEMBL10280755 | 0.81 | PSIP1 (0.54) | KMT2AHTTNPSR1MMP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |