Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867889 | 0.91 | HTT (0.51) | EPHX2L3MBTL1ALDH1A1LMNAP4HTM | |
| SCHEMBL7874583 | 0.91 | NPC1 (0.45) | EPHX2P4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL7867912 | 0.91 | EGFR (0.47) | EPHX2ALDH1A1P4HTMGABRA5 | |
| SCHEMBL7871609 | 0.91 | P4HTM (0.55) | P4HTMGABRA5NAMPT | |
| SCHEMBL7867808 | 0.90 | HSP90AA1 (0.44) | EPHX2ALDH1A1P4HTMOPRK1GABRA5 | |
| SCHEMBL7870523 | 0.90 | MEN1 (0.47) | ALDH1A1LMNAP4HTMOPRM1OPRD1 | |
| SCHEMBL7871570 | 0.88 | EGFR (0.45) | EPHX2P4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL7862839 | 0.87 | SMN1; SMN2 (0.48) | ALDH1A1LMNAP4HTMNAMPT | |
| SCHEMBL7869459 | 0.87 | MCL1 (0.52) | P4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL7870461 | 0.86 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1LMNAP4HTMOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |