Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 10/20 | 0.40 |
| ▸ | HTR1B | P28222 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655667 | 0.77 | NOTUM (0.41) | NOTUMGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL28381050 | 0.73 | HTR1D (0.37) | HTR1DHTR1BCYP1A2AHRPARP1 | |
| SCHEMBL3495344 | 0.69 | HTR1D (0.40) | HTR1DHTR1BAHRADRB1HTR6 | |
| SCHEMBL13497870 | 0.69 | ALDH1A1 (0.48) | NOTUMGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5365445 | 0.69 | DRD2 (0.37) | NOTUMPARP1 | |
| SCHEMBL2398840 | 0.68 | AHR (0.52) | HTR1DHTR1BAHRADRB1HTR6 | |
| SCHEMBL4382926 | 0.68 | NOTUM (0.42) | NOTUMGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7617146 | 0.67 | PNMT (0.49) | HTR1DHTR1B | |
| SCHEMBL582334 | 0.67 | NOTUM (0.46) | NOTUMKDM4EMEN1CYP1A2HPGD | |
| SCHEMBL31727562 | 0.67 | HTR1D (0.53) | HTR1DHTR1BPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54130597-A | — | — | None | — | — | JP | disclosed |
| JP-54130598-A | — | — | None | — | — | JP | disclosed |
| EP-4598586-A1 | DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF | Ambrx, Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024077277-A1 | DRUG LINKERS AND ANTIBODY CONJUGATES THEREOF | AMBRX, INC. (US) | 2024-04-11 | — | — | WO | disclosed |
| CN-116348614-A | Switching oligonucleotides | 牛津大学创新有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-103764843-B | For the method and composition for the risk for determining heart failure or heart failure | 罗塞塔金诺米克斯有限公司 | 2017-09-08 | — | — | CN | disclosed |
| US-6312925-B1 | EFFICIENT TARGETING AND MODIFICATION OF SEQUENCES IN DUPLEX DNA BY USING OLIGONUCLEOTIDE HAVING FIRST DOMAIN WHICH LOCALIZES TO VICINITY OF TARGET AND SECOND DOMAIN HAVING ATTACHED AGENT CAPABLE OF MODIFYING THE TARGET | EPOCH PHARMACEUTICALS, INC. | 2001-11-06 | — | — | US | disclosed |
| JP-S54130598-A | PREPARATION OF 1,2-DIHYDRO-3H-PYRROLO3,2-EINDOLE DERIVATIVE | MITSUI TOATSU CHEM INC | 1979-10-09 | — | — | JP | disclosed |
| JP-S54130597-A | PREPARATION OF 1,2-DIHYDRO-3H-PYRROLO3,2-EINDOLE DERIVATIVE | MITSUI TOATSU CHEM INC | 1979-10-09 | — | — | JP | disclosed |