Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865965 | 0.80 | TSHR (0.45) | HTTTDP1ALDH1A1MAPTGAA | |
| SCHEMBL2596015 | 0.79 | CHEK1 (0.46) | CHEK1SMN1; SMN2TDP1NQO2MTNR1A | |
| SCHEMBL11555366 | 0.79 | HTT (0.55) | HTTTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL3339987 | 0.79 | HMGCR (0.44) | SMN1; SMN2TDP1MAPTGAAKDM4E | |
| SCHEMBL6375580 | 0.79 | HTT (0.55) | HTTTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL6573968 | 0.78 | RAB9A (0.55) | CHEK1SMN1; SMN2HTTTDP1ALDH1A1 | |
| SCHEMBL7868696 | 0.78 | CA2 (0.39) | HTTTDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL4799531 | 0.77 | HTT (0.58) | HTTTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL7865943 | 0.77 | L3MBTL1 (0.44) | HTTTDP1ALDH1A1LMNAMAPT | |
| SCHEMBL6815710 | 0.77 | HTT (0.58) | HTTTDP1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306179-B1 | FOR DYEING HAIR | L'OREAL S.A. (FR) | 2001-10-23 | — | — | US | disclosed |
| EP-0911317-B1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | OREAL (FR) | 2000-09-13 | — | — | EP | disclosed |
| EP-0911317-A1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | L'OREAL (FR) | 1999-04-28 | — | — | EP | disclosed |