Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936903 | 0.85 | ESR2 (0.33) | ESR2MGAMGAASIMGAM2 | |
| SCHEMBL101757 | 0.81 | ACHE (0.41) | CYP1A2MEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL9648703 | 0.81 | ALOX5 (0.44) | ESR2ALOX5TAAR1TP53IDO1 | |
| SCHEMBL7733237 | 0.79 | CYP1A2 (0.38) | ESR2MGAMGAASIMGAM2 | |
| SCHEMBL2012944 | 0.79 | MGAM (0.42) | ESR2MGAMGAASIMGAM2 | |
| SCHEMBL16058080 | 0.79 | ALOX5 (0.42) | ESR2ALOX5TAAR1TP53IDO1 | |
| SCHEMBL10939277 | 0.79 | AHR (0.45) | GAAALDH1A1IDO1 | |
| SCHEMBL7006949 | 0.79 | ALOX5 (0.42) | ESR2ALOX5TAAR1TP53IDO1 | |
| SCHEMBL16719910 | 0.79 | ALOX5 (0.55) | ESR2ALOX5TAAR1TP53 | |
| SCHEMBL9716169 | 0.78 | TAAR1 (0.41) | ESR2GAAALOX5KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329135-B1 | LIGHT INSENSITIVE ORGANIC SILVER SALT ON A SUPPORT | KONICA CORPORATION (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1058151-A1 | Silver halide photothermographic material | KONICA CORPORATION (JP) | 2000-12-06 | — | — | EP | disclosed |
| EP-0036387-B1 | PROCESS FOR THE PREPARATION OF HYDRAZONO-ISOINDOLINES | CIBA-GEIGY AG (CH) | 1986-01-22 | — | — | EP | disclosed |
| EP-0036388-B1 | ISOINDOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-02-15 | — | — | EP | disclosed |
| US-4414395-A | REACTING AN IMINOISOINDOLE WITH HYDRAZINE | CIBA-GEIGY CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |