SCHEMBL10936903

SCHEMBL10936903

Cc1ccc[c]c1-c1cc(Cl)cc(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.33
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.31
CNR2 P34972 3/20 0.30
CNR1 P21554 2/20 0.30
CYP1A2 P05177 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7873510 0.85 ESR2 (0.46) ESR2MGAMGAASIMGAM2
SCHEMBL7733237 0.82 CYP1A2 (0.38) ESR2MGAMGAASIMGAM2
SCHEMBL10939277 0.78 AHR (0.45) GAASMN1; SMN2
SCHEMBL6581072 0.77 LMNA (0.35) GAASMN1; SMN2CYP1A2
SCHEMBL2012933 0.77 ACHE (0.37) MGAMGAASIMGAM2
SCHEMBL9649078 0.77 TSHR (0.31) TSHRRXRARXRB
SCHEMBL28360893 0.77 L3MBTL1 (0.35) GAATSHRCYP1A2RXRARXRB
SCHEMBL2884608 0.76 ACHE (0.42) TSHRCYP1A2
SCHEMBL11659071 0.76 TSHR (0.31) TSHR
SCHEMBL981110 0.75 TSHR (0.39) ESR2SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4524168-A AZO DYES CIBA-GEIGY CORPORATION (US) 1985-06-18 US disclosed