Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593112 | 0.84 | KDM4E (0.52) | KDM4ENPC1RAB9APOLBATM | |
| SCHEMBL7873581 | 0.83 | KDM4E (0.49) | KDM4ENPC1RAB9APOLBATM | |
| SCHEMBL7873556 | 0.81 | KDM4E (0.47) | KDM4ENPC1RAB9APOLBATM | |
| SCHEMBL16804872 | 0.80 | RAD51 (0.47) | NPC1RAB9ARAD51ADORA3CTSS | |
| SCHEMBL7526568 | 0.78 | ALDH1A1 (0.56) | KDM4ENPC1RAB9APOLBALDH1A1 | |
| SCHEMBL15533905 | 0.78 | RAD51 (0.45) | KDM4ENPC1RAB9APOLBRAD51 | |
| SCHEMBL3561445 | 0.78 | ALDH1A1 (0.47) | KDM4ENPC1RAB9APOLBRAD51 | |
| SCHEMBL19262265 | 0.78 | RAD51 (0.45) | KDM4ENPC1RAB9ARAD51ADORA3 | |
| SCHEMBL5646863 | 0.76 | POLB (0.51) | KDM4ENPC1RAB9APOLBATM | |
| SCHEMBL19805930 | 0.75 | SDHB (0.57) | KDM4ENPC1RAB9APOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313072-B1 | Herbicidal 2-aryloxy-or 2-arylthio-6-arylpyrimidines | AMERICAN CYANAMID COMPANY | 2001-11-06 | — | — | US | disclosed |