Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 2/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829389 | 0.82 | NPC1 (0.44) | NPC1RAB9AATMALDH1A1MEN1 | |
| SCHEMBL7873519 | 0.81 | KDM4E (0.50) | KDM4ENPC1RAB9APOLBATM | |
| SCHEMBL5593112 | 0.81 | KDM4E (0.52) | KDM4ENPC1RAB9APOLBATM | |
| SCHEMBL7528863 | 0.80 | ALDH1A1 (0.61) | KDM4ENPC1RAB9AATMALDH1A1 | |
| SCHEMBL7873581 | 0.79 | KDM4E (0.49) | KDM4ENPC1RAB9APOLBATM | |
| SCHEMBL12888330 | 0.78 | ADORA3 (0.40) | KDM4ENPC1RAB9APOLBATM | |
| SCHEMBL19805780 | 0.74 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL10698921 | 0.73 | GAA (0.47) | KDM4EALDH1A1HSD17B10HPGDMEN1 | |
| SCHEMBL16013822 | 0.73 | LOXL2 (0.45) | KDM4ENPC1RAB9AIDO1TDO2 | |
| SCHEMBL16013131 | 0.73 | CTSS (0.49) | KDM4ENPC1RAB9AIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313072-B1 | Herbicidal 2-aryloxy-or 2-arylthio-6-arylpyrimidines | AMERICAN CYANAMID COMPANY | 2001-11-06 | — | — | US | disclosed |