Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | CASP9 | P55211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994243 | 0.85 | NOS3 (0.49) | NOS3NOS1NOS2PDE3BPDE3A | |
| SCHEMBL9279571 | 0.76 | KDM4E (0.45) | NOS3NOS1NOS2CYP1A2ALDH1A1 | |
| SCHEMBL19968930 | 0.74 | NPSR1 (0.35) | — | |
| SCHEMBL14141233 | 0.70 | NOS3 (0.54) | NOS3NOS1NOS2RAB9A | |
| SCHEMBL10696135 | 0.68 | HRH4 (0.35) | NOS3NOS1NOS2PDE3BPDE3A | |
| SCHEMBL8994244 | 0.67 | PDE3B (0.42) | PDE3BPDE3ACYP1A2ALDH1A1MAOA | |
| SCHEMBL30804593 | 0.66 | MAOA (0.38) | AHRALDH1A1MAOANPC1MAPT | |
| SCHEMBL3348606 | 0.66 | MAOA (0.38) | AHRALDH1A1MAOANPC1MAPT | |
| SCHEMBL35438 | 0.65 | NOS3 (0.48) | NOS3NOS1NOS2PDE3BPDE3A | |
| SCHEMBL3616940 | 0.65 | NOS3 (0.48) | NOS3NOS1NOS2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667397-B1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | BAYER AG (US) | 2001-10-04 | — | — | EP | claimed |
| EP-0667397-A1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1995-08-16 | — | — | EP | claimed |
| US-5393615-A | Electrode with acridinone or dibenzoxazepinone mediator on surface | MILES INC. (US) | 1995-02-28 | — | — | US | claimed |
| JP-7310194-A | — | — | None | — | — | JP | disclosed |
| US-11913884-B2 | Visible light-activated dyes and methods of use thereof | WILLIAM MARSH RICE UNIVERSITY (US) | 2024-02-27 | — | — | US | disclosed |
| US-20200271587-A1 | VISIBLE LIGHT-ACTIVATED DYES AND METHODS OF USE THEREOF | WILLIAM MARSH RICE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
| JP-H07310194-A | MEDIATOR SUITABLE FOR ELECTROCHEMICAL REGENERATION OF NADH, NADPH OR ANALOGS THEREOF | BAYER CORP | 1995-11-28 | — | — | JP | disclosed |
| EP-0667397-A1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1995-08-16 | — | — | EP | disclosed |
| US-5393615-A | Electrode with acridinone or dibenzoxazepinone mediator on surface | MILES INC. (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0270946-A2 | Chromogenic acridinone enzyme substrates | MILES INC. (US) | 1988-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200271587-A1 | VISIBLE LIGHT-ACTIVATED DYES AND METHODS OF USE THEREOF | HCCS, CLTB, ALDH1A2 | NOS3 949/4885NOS1 1884/4885NOS2 1340/4885 |
| US-11913884-B2 | Visible light-activated dyes and methods of use thereof | HCCS, CLTB, ALDH1A2 | NOS3 949/4885NOS1 1884/4885NOS2 1340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.