Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647785 | 0.87 | ACHE (0.54) | BCHEACHECYP3A4LMNAL3MBTL1 | |
| SCHEMBL10110960 | 0.84 | ALOX5 (0.46) | PPARGPPARASMN1; SMN2L3MBTL1 | |
| SCHEMBL8403516 | 0.84 | ALOX5 (0.46) | PPARGPPARASMN1; SMN2L3MBTL1 | |
| SCHEMBL7871801 | 0.84 | PPARG (0.43) | PPARGPPARABCHEACHEL3MBTL1 | |
| SCHEMBL7169569 | 0.83 | AOC3 (0.56) | L3MBTL1 | |
| SCHEMBL715536 | 0.79 | CYP3A4 (0.56) | ACHECYP3A4LMNANPC1RAB9A | |
| SCHEMBL11606793 | 0.78 | CYP3A4 (0.54) | ACHECYP3A4LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8403319 | 0.78 | CYSLTR2 (0.46) | CYP3A4LMNASMN1; SMN2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11192619 | 0.77 | L3MBTL1 (0.51) | ACHECYP3A4LMNAL3MBTL1HTT | |
| SCHEMBL10359989 | 0.77 | MAPK1 (0.53) | PPARGPPARACYP3A4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316405-B1 | CYCLOSPORIN A, POLYPEPTIDES, COMPONENT OF AMYLOID PLAQUES FOUND IN NEUROLOGICAL DISORDERS SUCH AS ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, AND AMYOTROPHIC LATERAL SCLEROSIS. THE CONJUGATES ARE USEFUL IN THE TREATMENT OF NEUROLOGICAL | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2001-11-13 | — | — | US | disclosed |