Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934115 | 0.86 | KDM4E (0.45) | KDM4EMAPTL3MBTL1ESR1CYP19A1 | |
| SCHEMBL798050 | 0.85 | ESR1 (0.58) | KDM4EMAPTL3MBTL1ESR1CYP19A1 | |
| SCHEMBL15751641 | 0.81 | KDM4E (0.51) | KDM4EMAPTL3MBTL1SLC16A3SLC16A1 | |
| SCHEMBL30777576 | 0.78 | MAPT (0.56) | KDM4EMAPTL3MBTL1SLC16A3SLC16A1 | |
| SCHEMBL787535 | 0.78 | MAPT (0.56) | KDM4EMAPTL3MBTL1SLC16A3SLC16A1 | |
| SCHEMBL798358 | 0.78 | CYP2C19 (0.46) | KDM4ECYP1A2CYP2C19RAB9AALDH1A1 | |
| SCHEMBL8797884 | 0.74 | HRH1 (0.51) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2HRH1 | |
| SCHEMBL788202 | 0.73 | HRH1 (0.45) | KDM4ECYP1A2CYP2C19ALDH1A1HTT | |
| SCHEMBL12475666 | 0.71 | TYR (0.60) | KDM4EMAPTALDH1A1HTTHRH1 | |
| SCHEMBL933038 | 0.70 | NPSR1 (0.55) | MAPTCYP1A2CYP2C19ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451781-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | Givaudan SA (CH) | 2012-05-16 | — | — | EP | claimed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | claimed |
| EP-2531489-A1 | OXALAMIDE DERIVATIVE AS UMAMI FLAVOURING AGENT | Givaudan SA (CH) | 2012-12-12 | — | — | EP | disclosed |
| EP-2451781-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | Givaudan SA (CH) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011095533-A1 | OXALAMIDE DERIVATIVE AS UMAMI FLAVOURING AGENT | GIVAUDAN SA (CH) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | disclosed |