Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 13/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875910 | 1.00 | OPRK1 (0.43) | OPRK1OPRD1OPRM1ESR1ESR2 | |
| SCHEMBL26451670 | 0.85 | ESR1 (0.39) | ESR1ESR2 | |
| SCHEMBL7420161 | 0.78 | OPRD1 (0.56) | OPRK1OPRD1OPRM1 | |
| SCHEMBL7420165 | 0.78 | OPRD1 (0.56) | OPRK1OPRD1OPRM1 | |
| SCHEMBL24305562 | 0.74 | OPRD1 (0.55) | OPRK1OPRD1OPRM1ESR1ESR2 | |
| SCHEMBL15577821 | 0.72 | SLC7A5 (0.47) | OPRK1OPRD1OPRM1ESR1ESR2 | |
| SCHEMBL29257469 | 0.72 | TRPA1 (0.40) | — | |
| SCHEMBL24565100 | 0.71 | ESR1 (0.44) | ESR1ESR2 | |
| SCHEMBL983099 | 0.71 | SLC6A2 (0.55) | ESR1ESR2 | |
| SCHEMBL20425314 | 0.70 | ESR1 (0.55) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941212-B1 | ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES | DEGUSSA (DE) | 2001-03-21 | — | — | EP | claimed |
| EP-0941212-A1 | ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES | Degussa-Hüls Aktiengesellschaft (DE) | 1999-09-15 | — | — | EP | claimed |
| WO-1998022415-A1 | ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES | Degussa-Hüls Aktiengesellschaft (DE) | 1998-05-28 | — | — | WO | claimed |
| EP-0941212-B1 | ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES | DEGUSSA (DE) | 2001-03-21 | — | — | EP | disclosed |
| EP-0941212-A1 | ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES | Degussa-Hüls Aktiengesellschaft (DE) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998022415-A1 | ENANTIOSELECTIVE CATALYTIC REDUCTION OF KETONES | Degussa-Hüls Aktiengesellschaft (DE) | 1998-05-28 | — | — | WO | disclosed |