Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876366 | 0.89 | MIF (0.47) | NPC1RAB9ATDP1SMN1; SMN2POLB | |
| SCHEMBL7872649 | 0.78 | EGFR (0.41) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL27657933 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL2004568 | 0.72 | TSHR (0.43) | EPHX2NR1H4NPC1RAB9ALMNA | |
| SCHEMBL5372 | 0.72 | MIF (0.67) | ALDH1A1ALOX15MAPTSMN1; SMN2CA1 | |
| SCHEMBL7867578 | 0.71 | RAB9A (0.52) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7872596 | 0.71 | RAB9A (0.52) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| Phenylacetic Acid SCHEMBL7872638 | 0.70 | KDM4E (0.52) | NPC1RAB9AL3MBTL1ALDH1A1TDP1 | |
| Terephthalic Acid SCHEMBL8989156 | 0.67 | CA1 (0.74) | NR4A2RXRARXRBNPC1RAB9A | |
| SCHEMBL8459965 | 0.66 | RXRA (1.00) | NR4A2RXRARXRBEPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316623-B1 | USEFUL FOR SCREENING IN BIOLOGICAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2001-11-13 | — | — | US | disclosed |