Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877387 | 0.89 | ALDH1A1 (0.55) | ALDH1A1HTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL7877347 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL7879555 | 0.85 | TDP1 (0.47) | ALDH1A1HTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL7879544 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL7879552 | 0.79 | CYP19A1 (0.64) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7877032 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL7875230 | 0.74 | TBXAS1 (0.37) | TBXAS1 | |
| SCHEMBL7877318 | 0.72 | CA9 (0.41) | SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL9021230 | 0.72 | CA9 (0.38) | SMN1; SMN2 | |
| SCHEMBL7876907 | 0.71 | TBXAS1 (0.34) | HTTSMN1; SMN2LMNATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326500-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | ABBOTT LABORATORIES | 2001-12-04 | — | — | US | disclosed |
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |
| US-6031109-A | Phenoxy-, phenylthio-, benzoyl-alkyleneaminoalkylene-imidazole derivatives as therapeutic agents | KNOLL AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000493-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |