Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | ACLY | P53396 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12459539 | 0.88 | TSHR (0.54) | MCL1TSHRHSD17B10BRD4ACLY | |
| SCHEMBL12027616 | 0.79 | HTT (0.68) | TSHRHSD17B10ACLYKMT2ACCR2 | |
| SCHEMBL25244870 | 0.78 | MEN1 (0.77) | MCL1HSD17B10BRD4KMT2ARXFP1 | |
| SCHEMBL12655168 | 0.77 | LMNA (0.58) | TSHRHSD17B10ACLYKMT2ATHRB | |
| SCHEMBL21135363 | 0.77 | KMT2A (0.56) | TSHRHSD17B10ACLYKMT2ACCR2 | |
| SCHEMBL6717132 | 0.77 | ACLY (0.54) | TSHRHSD17B10BRD4ACLYCCR2 | |
| SCHEMBL18359166 | 0.76 | RXFP1 (0.50) | MCL1TSHRBRD4KMT2ARXFP1 | |
| SCHEMBL15881204 | 0.76 | CA1 (0.50) | MCL1TSHRHSD17B10BRD4KMT2A | |
| SCHEMBL7591598 | 0.76 | CCR2 (0.62) | MCL1ACLYCCR2POLB | |
| SCHEMBL10626704 | 0.75 | PTGS2 (0.56) | TSHRHSD17B10ACLYKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010129570-A1 | SOLID FORMS OF SULFONAMIDES AND AMINO ACIDS | PLEXXIKON, INC. (US) | 2010-11-11 | — | — | WO | disclosed |