Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607563 | 0.79 | HTR1A (0.39) | — | |
| SCHEMBL7614024 | 0.77 | ESR2 (0.42) | ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL8865538 | 0.75 | ESR2 (0.41) | ESR1ESR2 | |
| SCHEMBL8865200 | 0.70 | ESR1 (0.44) | ESR1ESR2 | |
| SCHEMBL8865311 | 0.70 | ALOX15 (0.51) | — | |
| SCHEMBL7866083 | 0.70 | PARP1 (0.41) | — | |
| SCHEMBL27386671 | 0.69 | CYP19A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL8865276 | 0.69 | ALOX15 (0.50) | — | |
| SCHEMBL7607412 | 0.68 | DRD2 (0.30) | — | |
| SCHEMBL8986500 | 0.68 | ADRA2A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313311-B1 | ADRENERGIC STIMULANTS FOR POTENTIATING ANESTHETICS PRIOR TO SURGERY; HYPOTENSIVE AGENTS, ANALGESICS, ANTIISCHEMIC AGENTS; NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | ORION CORPORATION (FI) | 2001-11-06 | — | — | US | disclosed |
| EP-0888309-A1 | IMIDAZOLE DERIVATIVES HAVING AFFINITY FOR ALPHA2 RECEPTORS ACTIVITY | ORION CORPORATION (FI) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997012874-A1 | IMIDAZOLE DERIVATIVES HAVING AFFINITY FOR ALPHA2 RECEPTORS ACTIVITY | Orion-Yhtymä Oy (FI) | 1997-04-10 | — | — | WO | disclosed |