Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878460 | 0.86 | HPGD (0.39) | TSHRCXCL8L3MBTL1NPSR1PTGDR2 | |
| SCHEMBL10338678 | 0.83 | TSHR (0.41) | TSHRCXCL8L3MBTL1NPSR1PTGDR2 | |
| SCHEMBL6006352 | 0.83 | HTR1A (0.46) | TSHRCXCL8L3MBTL1NPSR1THRA | |
| SCHEMBL5587910 | 0.83 | GAA (0.38) | CXCL8L3MBTL1NPSR1AKR1B1SMN1; SMN2 | |
| SCHEMBL1395495 | 0.82 | EPHX1 (0.51) | TSHRCXCL8L3MBTL1PTGDR2ALDH1A1 | |
| SCHEMBL47951 | 0.82 | L3MBTL1 (0.48) | TSHRL3MBTL1NPSR1ALDH1A1THRA | |
| SCHEMBL5147274 | 0.80 | HPGD (0.38) | L3MBTL1ALDH1A1TP53HTTKMT2A | |
| SCHEMBL9616117 | 0.80 | KDM4E (0.44) | TSHRCXCL8L3MBTL1NPSR1PTGDR2 | |
| SCHEMBL611228 | 0.80 | CXCL8 (0.42) | TSHRCXCL8L3MBTL1NPSR1PTGDR2 | |
| SCHEMBL609103 | 0.80 | CXCL8 (0.42) | TSHRCXCL8L3MBTL1NPSR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107619392-B | 1H-indazole-4-ether compounds and use thereof as IDO inhibitors | 西华大学 | 2021-01-01 | — | — | CN | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |