SCHEMBL609103

SCHEMBL609103

O=C(O)Oc1ccccc1CCl

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CXCL8 P10145 2/20 0.42
PPARA Q07869 2/20 0.40
TP53 P04637 1/20 0.40
HTT P42858 1/20 0.40
TSHR P16473 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TRPA1 O75762 1/20 0.38
MAPK1 P28482 1/20 0.38
GSK3B P49841 1/20 0.38
HIF1A Q16665 1/20 0.38
PPARG P37231 1/20 0.37
CHRM1 P11229 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
FABP4 P15090 1/20 0.36
FABP5 Q01469 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28987932 0.87 PPARG (0.36) CXCL8PPARATP53HTTTSHR
SCHEMBL609102 0.86 CXCL8 (0.40) CXCL8PPARATP53HTTTSHR
Benzene SCHEMBL3150461 0.85 PTGS2 (0.55) PPARATSHRL3MBTL1ALDH1A1MAPK1
SCHEMBL606945 0.85 NPSR1 (0.41) CXCL8TP53HTTTSHRL3MBTL1
SCHEMBL5665826 0.84 CXCL8 (0.39) CXCL8PPARATP53HTTTSHR
SCHEMBL10338678 0.83 TSHR (0.41) CXCL8TP53HTTTSHRL3MBTL1
SCHEMBL6006352 0.83 HTR1A (0.46) CXCL8TSHRL3MBTL1NPSR1THRA
SCHEMBL28987934 0.83 FABP4 (0.36) CXCL8PPARATP53HTTTSHR
SCHEMBL5589283 0.83 IDO1 (0.37) CXCL8PPARATP53HTTTSHR
SCHEMBL248688 0.82 PTGS2 (0.52) PPARATSHRALDH1A1MAPK1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20230099694-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-03-30 US disclosed
CN-110233290-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2023-03-07 CN disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
CN-110212235-B Lithium secondary battery electrolyte capable of reducing battery impedance and lithium secondary battery thereof 广州天赐高新材料股份有限公司 2022-04-08 CN disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
CN-112803067-A Electrolyte and lithium secondary battery comprising same 广州天赐高新材料股份有限公司 2021-05-14 CN disclosed
US-20210052575-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2021-02-25 US disclosed
EP-2012386-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEM CORP (JP) 2020-12-23 EP disclosed
CN-106848406-B Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery 三菱化学株式会社 2020-09-11 CN disclosed
CN-101432923-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP (JP) 2009-05-13 CN disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
CN-101248552-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery using the same MITSUBISHI CHEM CORP (JP) 2008-08-20 CN disclosed
EP-1940818-A1 AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS Pharmaleads (FR) 2008-07-09 EP disclosed
CN-101218706-A Nonaqueous electrolyte solution, nonaqueous electrolyte secondary battery, and carbonate compound MITSUBISHI CHEM CORP (JP) 2008-07-09 CN disclosed
US-20080102375-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2008-05-01 US disclosed
EP-1898485-A1 NONAQUEOUS ELECTROLYTE, AND RECHARGEABLE BATTERY WITH NONAQUEOUS ELECTROLYTE Mitsubishi Chemical Corporation (JP) 2008-03-12 EP disclosed
WO-2007048787-A1 AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS PHARMALEADS (FR) 2007-05-03 WO disclosed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed
US-4059615-A INSECTICIDE, POLYMER INTERMEDIATE HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230099694-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS SUZ12, BRPF3, BRD4 CXCL8 3940/4885PPARA 78/4885TP53 2009/4885
US-20210052575-A1 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS SUZ12, SULT2A1, CYP4Z1 CXCL8 3967/4885PPARA 53/4885TP53 2807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.