Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878466 | 0.86 | TSHR (0.40) | HPGDKDM4EHSD17B10TSHRTHRA | |
| SCHEMBL47950 | 0.81 | L3MBTL1 (0.50) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL3342292 | 0.81 | EPHX1 (0.53) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL29587376 | 0.81 | L3MBTL1 (0.50) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL609102 | 0.79 | CXCL8 (0.40) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL611227 | 0.79 | CXCL8 (0.40) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL3289983 | 0.78 | CXCL8 (0.59) | CXCL8L3MBTL1 | |
| SCHEMBL608097 | 0.76 | MTNR1A (0.44) | HPGDKDM4EHSD17B10MTNR1AMTNR1B | |
| SCHEMBL29581614 | 0.76 | THRA (0.53) | MTNR1AMTNR1BTHRATHRBNPSR1 | |
| SCHEMBL729676 | 0.76 | THRA (0.53) | MTNR1AMTNR1BTHRATHRBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107619392-B | 1H-indazole-4-ether compounds and use thereof as IDO inhibitors | 西华大学 | 2021-01-01 | — | — | CN | disclosed |
| WO-2001056358-A2 | ENHANCED PROPERTIED PESTICIDES | ROHM AND HAAS COMPANY (US) | 2001-08-09 | — | — | WO | disclosed |