Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7878241 | 0.85 | KCNA5 (0.37) | ABCC1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL6937428 | 0.81 | ITGB3 (0.40) | ITGB3ITGA2BHPGDPRSS1TMPRSS15 | |
| SCHEMBL6938684 | 0.80 | ITGB3 (0.43) | MAPTALDH1A1ITGB3ITGA2BLMNA | |
| SCHEMBL7878251 | 0.76 | PRSS1 (0.35) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL6939377 | 0.74 | SELP (0.36) | ITGB3ITGA2B | |
| SCHEMBL6940902 | 0.74 | MEP1B (0.40) | ITGB3ITGA2BPRSS1TMPRSS15KMT2A | |
| SCHEMBL6938012 | 0.68 | NPY4R (0.32) | — | |
| SCHEMBL233797 | 0.67 | KMT2A (0.57) | ABCC1MAPTKDM4EALDH1A1POLB | |
| Benzene SCHEMBL27690342 | 0.67 | KMT2A (0.57) | ABCC1MAPTKDM4EALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL6013658 | 0.65 | KMT2A (0.55) | ABCC1MAPTKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326403-B1 | CARDIOVASCULAR DISORDERS | MERCK PATENT GESELLSCHAFT MIT (DE) | 2001-12-04 | — | — | US | disclosed |