Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 4/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.32 |
| ▸ | NPY1R | P25929 | 3/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937672 | 0.77 | EPHX2 (0.37) | NPY4RNPY5RNPY1RNPY2REPHX2 | |
| SCHEMBL6940902 | 0.70 | MEP1B (0.40) | — | |
| SCHEMBL7878241 | 0.70 | KCNA5 (0.37) | — | |
| SCHEMBL7416968 | 0.68 | NPY4R (0.36) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL6937428 | 0.68 | ITGB3 (0.40) | — | |
| SCHEMBL7878251 | 0.68 | PRSS1 (0.35) | — | |
| SCHEMBL7879657 | 0.68 | ABCC1 (0.39) | — | |
| SCHEMBL2107302 | 0.67 | PRMT1 (0.59) | ADRA1A | |
| SCHEMBL23732364 | 0.66 | KDM4A (0.41) | EPHX2ADRA1A | |
| Trifluoroacetic Acid SCHEMBL6756464 | 0.65 | HDAC3 (0.38) | NPY4RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326403-B1 | CARDIOVASCULAR DISORDERS | MERCK PATENT GESELLSCHAFT MIT (DE) | 2001-12-04 | — | — | US | claimed |
| EP-1097127-B1 | DIACYLHYDRAZINE DERIVATIVES AS INTEGRIN INHIBITORS | MERCK PATENT GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |
| US-6326403-B1 | CARDIOVASCULAR DISORDERS | MERCK PATENT GESELLSCHAFT MIT (DE) | 2001-12-04 | — | — | US | disclosed |