Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964590 | 0.93 | ALDH1A1 (0.44) | ALDH1A1PTK2BMEN1KMT2APKM | |
| SCHEMBL8496813 | 0.84 | PTK2B (0.47) | ALDH1A1PTK2BMEN1KMT2APKM | |
| SCHEMBL8498810 | 0.81 | KMT2A (0.50) | ALDH1A1PTK2BMEN1KMT2APKM | |
| SCHEMBL13505905 | 0.81 | MEN1 (0.50) | ALDH1A1PTK2BMEN1KMT2APKM | |
| SCHEMBL7049564 | 0.80 | MEN1 (0.49) | ALDH1A1PTK2BMEN1KMT2APKM | |
| SCHEMBL8496997 | 0.80 | MEN1 (0.49) | ALDH1A1PTK2BMEN1KMT2APKM | |
| SCHEMBL28189795 | 0.79 | MEN1 (0.50) | PTK2BMEN1KMT2APKMCXCL8 | |
| SCHEMBL6917578 | 0.78 | ALDH1A1 (0.54) | ALDH1A1PTK2BMEN1KMT2APKM | |
| SCHEMBL27810380 | 0.78 | PTK2B (0.43) | ALDH1A1PTK2BMEN1KMT2APKM | |
| SCHEMBL4644269 | 0.76 | GAA (0.47) | ALDH1A1MEN1KMT2ARECQLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281243-B1 | ANTIDEPRESSANTS, ANTISEROTONINE AGENT | AKZO NOBEL N.V. (NL) | 2001-08-28 | — | — | US | disclosed |