Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.35 |
| ▸ | NPY1R | P25929 | 6/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876318 | 0.88 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RC3AR1 | |
| SCHEMBL1765973 | 0.82 | PADI1 (0.43) | C3AR1 | |
| SCHEMBL7888149 | 0.80 | NOS1 (0.40) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| Hydrochloric Acid SCHEMBL7876078 | 0.79 | NOS1 (0.39) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| Trifluoroacetic Acid SCHEMBL8526449 | 0.77 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5RANPEP | |
| SCHEMBL3192649 | 0.76 | CYP1A2 (0.42) | — | |
| Arginine SCHEMBL26914670 | 0.74 | KIF11 (0.46) | NPY4RNPY1RNPY2RNPY5R | |
| Arginine SCHEMBL28268971 | 0.74 | OTC (0.53) | — | |
| SCHEMBL3834508 | 0.73 | LTA4H (0.38) | — | |
| SCHEMBL757757 | 0.73 | C3AR1 (0.39) | C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859607-A4 | GUANIDINO PROTEASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0859607-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1998024760-A1 | AMINOBENZENEDICARBOXYLIC ACID-BASED COMBINATORIAL LIBRARIES | GRAYBILL TODD L (US) | 1998-06-11 | — | — | WO | disclosed |
| WO-1997011693-A1 | GUANIDINO PROTEASE INHIBITORS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-04-03 | — | — | WO | disclosed |