Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360685 | 0.79 | HSD17B3 (0.43) | POLBDRD4DRD2CHRM2CHRM4 | |
| SCHEMBL6362811 | 0.79 | HRH1 (0.42) | POLBDRD4DRD2CHRM2CHRM4 | |
| SCHEMBL10132064 | 0.77 | ATAD2 (0.39) | POLBDRD4DRD2CHRM2CHRM4 | |
| SCHEMBL13041629 | 0.75 | SMN1; SMN2 (0.36) | GRM4MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL7885143 | 0.75 | ALDH1A1 (0.45) | POLBDRD4DRD2CHRM2CHRM4 | |
| SCHEMBL7886985 | 0.72 | C5AR1 (0.47) | — | |
| SCHEMBL16281091 | 0.71 | CHRM2 (0.43) | POLBDRD4DRD2CHRM2CHRM4 | |
| SCHEMBL10162607 | 0.71 | DRD2 (0.46) | POLBDRD4DRD2CHRM2CHRM4 | |
| SCHEMBL5113192 | 0.69 | HTR7 (0.53) | DRD4DRD2DRD3ATAD2HTR7 | |
| SCHEMBL30382092 | 0.69 | HTR7 (0.53) | DRD4DRD2DRD3ATAD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103306-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIVARAL AGENTS | ASTRAZENECA UK LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |