Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789678 | 0.96 | SCN9A (0.33) | SCN9A | |
| SCHEMBL2597088 | 0.93 | F10 (0.31) | IRAK4 | |
| SCHEMBL789216 | 0.86 | SLC6A9 (0.34) | IRAK4 | |
| SCHEMBL789299 | 0.83 | DPP4 (0.30) | — | |
| SCHEMBL2597109 | 0.83 | SLC6A9 (0.37) | — | |
| SCHEMBL790391 | 0.81 | BRD4 (0.33) | — | |
| SCHEMBL790469 | 0.80 | SCN9A (0.34) | SCN9A | |
| SCHEMBL788886 | 0.80 | SCN9A (0.34) | SCN9A | |
| SCHEMBL789443 | 0.75 | AKR1C3 (0.34) | — | |
| SCHEMBL797320 | 0.72 | BTK (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616074-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| EP-2571864-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2012037393-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011146335-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2011-11-24 | — | — | WO | disclosed |