Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789216 | 0.87 | SLC6A9 (0.34) | — | |
| SCHEMBL2597109 | 0.84 | SLC6A9 (0.37) | — | |
| SCHEMBL789053 | 0.83 | SCN9A (0.32) | — | |
| SCHEMBL2597088 | 0.82 | F10 (0.31) | — | |
| SCHEMBL790391 | 0.80 | BRD4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL789439 | 0.80 | SLC9A3 (0.32) | — | |
| SCHEMBL789678 | 0.79 | SCN9A (0.33) | DPP4 | |
| SCHEMBL789192 | 0.76 | GPR119 (0.40) | — | |
| Hydrochloric Acid SCHEMBL2597110 | 0.75 | GPR119 (0.40) | — | |
| SCHEMBL789443 | 0.74 | AKR1C3 (0.34) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616074-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037393-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2012-03-22 | — | — | WO | disclosed |