Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789053 | 0.93 | SCN9A (0.32) | IRAK4 | |
| SCHEMBL789678 | 0.89 | SCN9A (0.33) | F10 | |
| SCHEMBL789216 | 0.85 | SLC6A9 (0.34) | IRAK4 | |
| SCHEMBL789299 | 0.82 | DPP4 (0.30) | — | |
| SCHEMBL2597109 | 0.82 | SLC6A9 (0.37) | F10 | |
| SCHEMBL790391 | 0.80 | BRD4 (0.33) | F10 | |
| SCHEMBL788886 | 0.75 | SCN9A (0.34) | — | |
| SCHEMBL790469 | 0.75 | SCN9A (0.34) | — | |
| SCHEMBL789443 | 0.72 | AKR1C3 (0.34) | — | |
| SCHEMBL2597087 | 0.70 | FPR2 (0.39) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066869-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2013-05-10 | — | — | WO | disclosed |
| EP-2571864-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146335-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2011-11-24 | — | — | WO | disclosed |