Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Silicate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silicate SCHEMBL9140766 | 1.00 | — | — | |
| Silicate SCHEMBL1879984 | 1.00 | — | — | |
| Silicate SCHEMBL1888568 | 1.00 | — | — | |
| Silicate SCHEMBL10587233 | 1.00 | — | — | |
| Silicate SCHEMBL18663384 | 1.00 | — | — | |
| Silicate SCHEMBL6549352 | 0.94 | — | — | |
| Silicate SCHEMBL6394282 | 0.94 | — | — | |
| Silicate SCHEMBL6547206 | 0.94 | — | — | |
| Silicate SCHEMBL222412 | 0.94 | — | — | |
| Silicate SCHEMBL9056812 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043972-B1 | BIODIESEL PRODUCTION USING COMPOSITE CATALYSTS | UNIV IOWA STATE RES FOUND INC (US) | 2020-04-29 | — | — | EP | claimed |
| EP-2690076-A1 | Method for manufacturing multi-phase hydraulic binders | Cemex Research Group AG (CH) | 2014-01-29 | — | — | EP | claimed |
| JP-1120483-A | — | — | None | — | — | JP | disclosed |
| WO-2023017550-A1 | FIBERS CEMENT NANOCOMPOSITE AND MANUFACTURING METHOD THEREOF | ASADI MOHAMMAD (IR) | 2023-02-16 | — | — | WO | disclosed |
| EP-2043972-B1 | BIODIESEL PRODUCTION USING COMPOSITE CATALYSTS | UNIV IOWA STATE RES FOUND INC (US) | 2020-04-29 | — | — | EP | disclosed |
| CN-105541168-B | A kind of inorganic mineral waterproof activity masterbatch | 广州市晟晶环保建材有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-105541168-A | Inorganic mineral waterproof active master batch | GUANGZHOU SHENGJING ENV BUILDING MAT CO LTD | 2016-05-04 | — | — | CN | disclosed |
| EP-2690076-A1 | Method for manufacturing multi-phase hydraulic binders | Cemex Research Group AG (CH) | 2014-01-29 | — | — | EP | disclosed |
| WO-2012037180-A1 | COEXTRUDED MULTILAYER FILM STRUCTURE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011163162-A2 | STABILIZED VINYLIDENE CHLORIDE COPOLYMER BLEND COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-12-29 | — | — | WO | disclosed |
| JP-2010235691-A | COATED POROUS INORGANIC PARTICLE AND MOLDED ARTICLE USING THE SAME | NIIGATA UNIV | 2010-10-21 | — | — | JP | disclosed |
| JP-H01120483-A | METAL GASKET MATERIAL AND ITS MANUFACTURE | NISSHIN STEEL CO LTD | 1989-05-12 | — | — | JP | disclosed |