Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL30552135 | 1.00 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CA1CA2CA7 | |
| Trifluoromethanesulfonic Acid SCHEMBL27902845 | 0.97 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CA1CA2CA7 | |
| Trifluoromethanesulfonic Acid SCHEMBL28220121 | 0.97 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CA1CA2CA7 | |
| Trifluoromethanesulfonic Acid SCHEMBL596728 | 0.97 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CA1CA2CA7 | |
| Trifluoromethanesulfonic Acid SCHEMBL28188456 | 0.91 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1CA1CA2CA7 | |
| Trifluoromethanesulfonic Acid SCHEMBL39465 | 0.89 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CA1CA2CA7 | |
| Trifluoromethanesulfonic Acid SCHEMBL295 | 0.89 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL3507077 | 0.89 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL3950101 | 0.89 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL25292879 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956321-B1 | PROCESS FOR PREPARING AXITINIB, PROCESS FOR PURIFYING THE INTERMEDIATE 2-((3-IODO-1H-INDAZOL-6-YL)THIO)-N-METHYLBENZAMIDE, PROCESS FOR PURIFYING AXITINIB VIA THE AXITINIB HCL SALT, SOLID FORM OF THE AXITINIB HCL SALT | SYNTHON BV (NL) | 2024-03-20 | — | — | EP | claimed |
| CN-115716805-A | Method for asymmetric catalytic synthesis of chiral pyrazolone derivative containing propargyl alcohol structural fragment | 重庆医科大学 | 2023-02-28 | — | — | CN | claimed |
| CN-115385948-A | Spiro-dihydrobenzothiole bisoxazoline compound, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2022-11-25 | — | — | CN | claimed |
| CN-110669097-B | Synthesis method of oleanoline derivative | 北京赫尔默技术有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-110669097-A | Synthesis method of oleanoline derivative | 北京赫尔默技术有限公司 | 2020-01-10 | — | — | CN | claimed |
| EP-2855419-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS | Boehringer Ingelheim International GmbH (DE) | 2015-04-08 | — | — | EP | claimed |
| WO-2013178575-A1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-05 | — | — | WO | claimed |
| CN-119371419-A | PKMYT1 kinase inhibitors | 杭州邦顺制药有限公司 | 2025-01-28 | — | — | CN | disclosed |
| US-20240199607-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | ASTEX THERAPEUTICS LIMITED (GB) | 2024-06-20 | — | — | US | disclosed |
| EP-4364570-A1 | HETEROCYCLIC COMPOUND AND RESISTANT HARMFUL ARTHROPOD-CONTROLLING METHOD FOR COMPOSITION CONTAINING SAME | Sumitomo Chemical Company Limited (JP) | 2024-05-08 | — | — | EP | disclosed |
| CN-115716805-B | Asymmetric catalytic synthesis method of chiral pyrazolone derivative containing propargyl alcohol structural fragment | 重庆医科大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-115716805-B | Asymmetric catalytic synthesis method of chiral pyrazolone derivative containing propargyl alcohol structural fragment | 重庆医科大学 | 2024-05-07 | — | — | CN | disclosed |
| US-11866428-B2 | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LIMITED (GB) | 2024-01-09 | — | — | US | disclosed |
| US-20040235667-A1 | Pyrazolyl-substituted thienyloxypyridines | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
| US-20040181075-A1 | Process of making chalcone derivatives | GENERAL ELECTRIC COMPANY | 2004-09-16 | — | — | US | disclosed |
| US-20040143139-A1 | Process for the production of aminodiphenylamines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | US | disclosed |
| EP-1432689-A1 | PYRAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF HYPER-PROLIFERATIVE DISORDERS | Bayer Corporation (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003090912-A9 | PYRROLO-TRIAZINE ANILINE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2004-01-08 | — | — | WO | disclosed |
| WO-2003090912-A1 | PYRROLO-TRIAZINE ANILINE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-06 | — | — | WO | disclosed |
| WO-2003027074-A1 | PYRAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF HYPER-PROLIFERATIVE DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143139-A1 | Process for the production of aminodiphenylamines | NUDT1, ITPA, NAAA | ALDH1A1 693/4885L3MBTL1 4675/4885CA1 3079/4885 |
| US-20040235667-A1 | Pyrazolyl-substituted thienyloxypyridines | HDHD5, CBR3, KCNH3 | ALDH1A1 2329/4885L3MBTL1 820/4885CA1 4430/4885 |
| US-20240199607-A1 | BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 | ALDH1A1 1493/4885L3MBTL1 1230/4885CA1 2764/4885 |
| US-11866428-B2 | Bicyclic heterocycle compounds and their uses in therapy | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CCNB1, CCNE1 | ALDH1A1 1493/4885L3MBTL1 1230/4885CA1 2764/4885 |
| US-20040181075-A1 | Process of making chalcone derivatives | CYP2B6, LSS, CYP2E1 | ALDH1A1 828/4885L3MBTL1 1678/4885CA1 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.