Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894602 | 0.87 | ALDH1A1 (0.51) | GAAMAPTALDH1A1ALOX12HPGD | |
| SCHEMBL7892210 | 0.74 | ALDH1A1 (0.52) | GAAALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL7365917 | 0.73 | ALDH1A1 (0.70) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7892193 | 0.73 | PDE4A (0.41) | LIPGGAAALDH1A1HPGDPDE4A | |
| SCHEMBL7894711 | 0.70 | ADORA1 (0.46) | GAAALDH1A1HPGDPDE4APDE4B | |
| SCHEMBL9168570 | 0.69 | NPSR1 (0.56) | GAAALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL7362478 | 0.68 | PDE4A (0.77) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7361626 | 0.67 | ALDH1A1 (0.56) | MAPTALDH1A1HPGDPDE4APDE4B | |
| SCHEMBL1252544 | 0.67 | PDE4A (0.50) | GAAALDH1A1HPGDPDE4APDE4B | |
| SCHEMBL7363014 | 0.67 | ALDH1A1 (0.59) | ALDH1A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180629-B1 | INDUCING OR PROMOTING APOPTOSIS AND FOR ARRESTING UNCONTROLLED NEOPLASTIC CELL PROLIFERATION, INCLUDING PRECANCEROUS AND CANCEROUS LESIONS | CELL PATHWAYS, INC. | 2001-01-30 | — | — | US | disclosed |