Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165637 | 0.91 | NPSR1 (0.56) | NPSR1GAAALDH1A1LMNAALOX5 | |
| SCHEMBL7366959 | 0.91 | L3MBTL1 (0.58) | NPSR1GAAALDH1A1LMNAALOX5 | |
| SCHEMBL7367332 | 0.88 | HTT (0.53) | NPSR1GAAALDH1A1LMNAALOX5 | |
| SCHEMBL7359405 | 0.87 | PDE4A (0.61) | NPSR1GAAALDH1A1LMNAKDM4E | |
| SCHEMBL7361949 | 0.87 | PDE4A (0.53) | NPSR1GAAALDH1A1ALOX5KDM4E | |
| SCHEMBL7363973 | 0.87 | NPSR1 (0.50) | NPSR1GAAALDH1A1LMNAALOX5 | |
| SCHEMBL7361460 | 0.86 | NPSR1 (0.49) | NPSR1GAAALDH1A1LMNAALOX5 | |
| SCHEMBL16535885 | 0.86 | ALDH1A1 (0.48) | NPSR1GAAALDH1A1LMNAPDE4A | |
| SCHEMBL9171807 | 0.84 | NPSR1 (0.75) | NPSR1GAAALDH1A1LMNAKDM4E | |
| SCHEMBL7366676 | 0.84 | NCOA1 (0.48) | NPSR1GAAALDH1A1LMNAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | claimed |
| JP-5279363-A | — | — | None | — | — | JP | disclosed |
| US-5405826-A | Herbicidal pyridopyridazinones and pyridopyridazinethiones | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-04-11 | — | — | US | disclosed |
| JP-H05279363-A | NEW HERBICIDE | RHONE POULENC AGRICULTURE LTD | 1993-10-26 | — | — | JP | disclosed |
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | disclosed |