Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592075 | 0.83 | KDM4E (0.49) | KDM4EPOLBALDH1A1MAPTLMNA | |
| SCHEMBL4050261 | 0.79 | POLB (0.55) | KDM4EPOLBALDH1A1MAPTLMNA | |
| SCHEMBL7893096 | 0.76 | KDM4E (0.53) | KDM4EPOLBALDH1A1MAPTLMNA | |
| SCHEMBL10531764 | 0.76 | POLB (0.43) | KDM4EPOLBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11307884 | 0.75 | ADRA2A (0.48) | KDM4EPOLBALDH1A1MAPTLMNA | |
| SCHEMBL8913612 | 0.74 | POLB (0.38) | KDM4EPOLBALDH1A1MAPTLMNA | |
| SCHEMBL11306358 | 0.74 | KMT2A (0.57) | KDM4EALDH1A1MAPTLMNAHSD17B10 | |
| SCHEMBL11313630 | 0.73 | KDM4E (0.55) | KDM4EPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL11326890 | 0.71 | IDH1 (0.37) | KDM4EPOLBALDH1A1MAPTHSD17B10 | |
| SCHEMBL10587273 | 0.71 | ALDH1A1 (0.49) | KDM4EPOLBALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177552-B1 | CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS | DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2001-01-23 | — | — | US | disclosed |
| EP-0489360-B1 | Water-soluble azocompounds, process for their preparation and their use as dyes | HOECHST AG (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0399411-B1 | Water soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AG (DE) | 1994-07-13 | — | — | EP | disclosed |
| EP-0381133-B1 | Water soluble azo compounds, method for their preparation and their use as dyestuffs | HOECHST AG (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0384276-B1 | Water soluble azo compounds, method for their preparation and their use as dyestuffs | HOECHST AG (DE) | 1993-11-10 | — | — | EP | disclosed |
| US-5216138-A | With vinyl sulfonyl group | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0489360-A1 | Water-soluble azocompounds, process for their preparation and their use as dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-5021559-A | Water-soluble azo compounds containing a fiber-reactive group of the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| US-5010180-A | Printing, dyeing | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0399411-A1 | Water soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-28 | — | — | EP | disclosed |
| EP-0384276-A1 | Water soluble azo compounds, method for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0381133-A1 | Water soluble azo compounds, method for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-08 | — | — | EP | disclosed |
| US-4659807-A | Water-soluble pyridone monoazo compounds suitable as fiber reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0181585-A2 | Fibre-reactive monoazo compounds, process for their preparation and their dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-21 | — | — | EP | disclosed |
| EP-0078009-B1 | WATER-SOLUBLE PYRIDONE AZO COMPOUNDS; PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-07 | — | — | EP | disclosed |
| EP-0078024-B1 | WATER-SOLUBLE PYRIDONE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0078009-A1 | Water-soluble pyridone azo compounds; process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-04 | — | — | EP | disclosed |