Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7895052 | 0.85 | ALDH1A1 (0.42) | ALDH1A1CYP2C9CYP2C19CYP3A4THRB | |
| SCHEMBL2793999 | 0.76 | THRB (0.39) | ALDH1A1CYP2C19THRBTSHRHCAR2 | |
| SCHEMBL351499 | 0.74 | THRB (0.45) | ALDH1A1CYP2C19CYP3A4THRBTSHR | |
| SCHEMBL6267673 | 0.74 | CYP3A4 (0.47) | ALDH1A1CYP2C9CYP2C19CYP3A4THRB | |
| SCHEMBL16486014 | 0.73 | CYP1A2 (0.46) | THRBHCAR2CYP1A2 | |
| SCHEMBL9646933 | 0.72 | CTSK (0.47) | THRBTSHRCYP1A2 | |
| SCHEMBL961985 | 0.72 | CYP1A2 (0.44) | THRBTSHRCYP1A2 | |
| SCHEMBL961692 | 0.72 | CYP2C9 (0.47) | ALDH1A1CYP2C9CYP2C19CYP3A4THRB | |
| SCHEMBL28660633 | 0.72 | ALDH1A1 (0.45) | ALDH1A1CYP2C9CYP2C19CYP3A4THRB | |
| SCHEMBL2362357 | 0.71 | CES2 (0.44) | ALDH1A1CYP2C19CYP3A4THRBHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184323-B1 | FOR OPHTHALMIC LENSES | ESSILOR INTERNATIONAL-COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-02-06 | — | — | US | disclosed |